Insect Nicotinic Acetylcholine Receptors


Free download. Book file PDF easily for everyone and every device. You can download and read online Insect Nicotinic Acetylcholine Receptors file PDF Book only if you are registered here. And also you can download or read online all Book PDF file that related with Insect Nicotinic Acetylcholine Receptors book. Happy reading Insect Nicotinic Acetylcholine Receptors Bookeveryone. Download file Free Book PDF Insect Nicotinic Acetylcholine Receptors at Complete PDF Library. This Book have some digital formats such us :paperbook, ebook, kindle, epub, fb2 and another formats. Here is The CompletePDF Book Library. It's free to register here to get Book file PDF Insect Nicotinic Acetylcholine Receptors Pocket Guide.
Log in to Wiley Online Library

Bruno Lapied 1 AuthorId : Author. Hide details. Abstract : Insect nicotinic acetylcholine nACh receptors are molecular targets of insecticides such as neonicotinoids that are used to control disease-carrying insects and agricultural pests. To date, several insect nACh receptor subunits have been identified, indicating different nACh receptor subtypes and pharmacological profiles. Because of the difficulty in expressing functional insect nACh receptors in heterologous systems, new research tools are needed.

Studies on insects resistant to the insecticide imidacloprid and on laboratory-generated hybrid and chimaeric nACh receptors in vitro have provided information about the molecular basis of receptor diversity, neonicotinoid resistance and selectivity. The carbamidomethylation of cysteine was considered as a fixed modification, and the conversion of N-terminal glutamine to pyroglutamic acid and methionine oxidation were considered as variable modifications.

All identified peptides had an ion score above the Mascot peptide identity threshold, and a protein was considered to be identified if at least one such unique peptide match was apparent for the protein. The information of the sequences has been released to the database of GeneBank. The cRNAs of all subunits were generated as described previously Xenopus oocyte preparation and cRNA injection were performed as described previously Differences in responses currents , I max and EC 50 values were analyzed by one-way ANOVA with at least three repeats different batches of oocytes from different frogs.

Multiple comparisons between the groups were performed using S-N-K method. Breer, H. Molecular-forms and subunit structure of the acetylcholine-receptor in the central-nervous-system of insects. Sattelle, D. Cholinergic nerve-terminals in the central-nervous-system of insects - molecular aspects of structure, function and regulation.

Matsuda, K. Neonicotinoids: Insecticides acting on insect nicotinic acetylcholine receptors. Trends Pharmacol. Geng, C. Cohen E. Nereistoxin - actions on a CNS acetylcholine-receptor ion channel in the cockroach Periplaneta americana. Harp, P. Nicotine and organophosphate insecticides: Potential for interactive toxicity. Liu, Z. Heteromeric co-assembly of two insect nicotinic acetylcholine receptor alpha subunits: Influence on sensitivity to neonicotinoid insecticides.

Bertrand, D. Physiological-properties of neuronal nicotinic receptors reconstituted from the vertebrate beta-2 subunit and Drosophila alpha-subunits.

A nicotinic acetylcholine receptor mutation conferring target-site resistance to imidacloprid in Nilaparvata lugens brown planthopper. Adams, M. The genome sequence of Drosophila melanogaster. Science , — Nene, V. Genome sequence of Aedes aegypti , a major arbovirus vector. Richards, S. The genome of the model beetle and pest Tribolium castaneum. Nature , — Miwa, J. Lynx1, an endogenous toxin-like modulator of nicotinic acetylcholine receptors in the mammalian CNS.

Neuron 23 , — Identification of two lynx proteins in Nilaparvata lugens and the modulation on insect nicotinic acetylcholine receptors. Yang, B. Selectivity of lynx proteins on insect nicotinic acetylcholine receptors in the brown planthopper, Nilaparvata lugens. Insect Mol. Lansdell, S. The Drosophila nicotinic acetylcholine receptor subunits d alpha 5 and d alpha 7 form functional homomeric and heteromeric ion channels.

BMC Neurosci.

Insect Nicotinic Acetylcholine Receptors

Skou, J. The na,k-atpase. Xie, Z. Heiny, J. Tomizawa, M. Novel neonicotinoid-agarose affinity column for Drosophila and musca nicotinic acetylcholine receptors. DeTomaso, A. Expression, targeting, and assembly of functional Na,K-ATPase polypeptides in baculovirus-infected insect cells. Martin, D. Mobasheri, A. Scheiner-Bobis, G. The sodium pump: Its molecular properties and mechanics of ion transport.


  • Diversity of insect nicotinic acetylcholine receptor subunits.?
  • Research Output.
  • Wolf-Rayet Stars: Observations, Physics, Evolution.

Shoaib, M. Antagonism of stimulus properties of nicotine by dihydro-beta-erythroidine dh beta e in rats. Psychopharmacology , — Blanco, G.

Diversity of insect nicotinic acetylcholine receptor subunits.

Na,K-ATPase subunit heterogeneity as a mechanism for tissue-specific ion regulation. Cho, S.

Protein-protein interaction networks: From interactions to networks. Kabbani, N.